Alongside eliminating any drawbacks your powers come with, you can turn them into strengths.
Whenever you encounter an effect that would naturally weaken or debilitate you as a result of the powers you possess, you are instead enhanced by the same margin.
For example, as a Kryptonian Green Kryptonite would amplify your power to put you as far away in strength from your normal form as you are to humans.
This applies automatically, however you can choose for it to not take effect if you wish for any reason.